Gene Knockout Research

A gene knockout is a genetic technique in which one of an organism's genes is made inoperative. Also known as knockout organisms or simply knockouts, they are used in learning about a gene that has been sequenced, but which has an unknown or incompletely known function. Researchers draw inferences from the difference between the knockout organism and normal individuals. The term also refers to the process of creating such an organism, as in "knocking out" a gene. The technique is essentially the opposite of a gene knockin. Knocking out two genes simultaneously in an organism is known as a double knockout. Similarly the terms triple knockout and quadruple knockouts are used to describe three or four knocked out genes, respectively. This article introduces recent research reports as references in the related studies. [Ma H, Young M, Yang Y. Gene Knockout Research Literatures. Rep Opinion 2015;7(12):69-92]. (ISSN: 15539873). http://www.sciencepub.net/report. 7. doi:10.7537/marsroj071215.07.